Publication | Open Access

Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535

Medicinal ChemistryClinical Candidate Ce-224,535BiochemistryMedicineNatural SciencesPharmacological AgentPharmacotherapy6-Azauracil SeriesP2x7 Receptor AntagonistsPharmacologyPharmaceutical ChemistryDrug Discovery