Kenneth G. Kraus

Biarylcarboxylic Acids and -amides:  Inhibition of Phosphodiesterase Type IV versus [³H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in the Ferret

Allen J. Duplantier, Michael S. Biggers, Robert Chambers et al. · Journal of Medicinal Chemistry · 1996 · 143 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535

Allen J. Duplantier, Mark A. Dombroski, Chakrapani Subramanyam et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and in vitro profile of a novel series of catechol benzimidazoles. The discovery of potent, selective phosphodiesterase type IV inhibitors with greatly attenuated affinity for the [3H]rolipram binding site

John B. Cheng, Kelvin Cooper, Allen J. Duplantier et al. · Bioorganic & Medicinal Chemistry Letters · 1995 · 45 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Pulmonary Eosinophilia in a Murine Model of Allergic Inflammation Is Attenuated by Small Molecule α4β1 Antagonists

Elizabeth M. Kudlacz, Carrie A Whitney, Catharine J. Andresen et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 39 citations

Life Sciences, Immunology, Pharmacology +17

SAR of a Series of 5,6-Dihydro-(9<i>H</i>)-pyrazolo[3,4-<i>c</i>]-1,2,4-triazolo[4,3-α]pyridines as Potent Inhibitors of Human Eosinophil Phosphodiesterase

Allen J. Duplantier, Elizabeth L. Bachert, John B. Cheng et al. · Journal of Medicinal Chemistry · 2006 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16