Michael S. Biggers

Biarylcarboxylic Acids and -amides:  Inhibition of Phosphodiesterase Type IV versus [³H]Rolipram Binding Activity and Their Relationship to Emetic Behavior in the Ferret

Allen J. Duplantier, Michael S. Biggers, Robert Chambers et al. · Journal of Medicinal Chemistry · 1996 · 143 citations · Full text

Novel nonpeptide agents potently block the C-type inactivated conformation of Kv1.3 and suppress T cell activation.

Angela Nguyen, John C. Kath, Douglas C. Hanson et al. · Molecular Pharmacology · 1996 · 99 citations

(+)-1-(3S,4R)-[3-(4-Phenylbenzyl)-4- hydroxychroman-7-yl]cyclopentane Carboxylic Acid, a Highly Potent, Selective Leukotriene B4 Antagonist with Oral Activity in the Murine Collagen-Induced Arthritis Model

Kevin M. Koch, Lawrence S. Melvin, Lawrence A. Reiter et al. · Journal of Medicinal Chemistry · 1994 · 54 citations · Full text

Pharmaceutical Science, Immunology, Altmetric Attention Score +18

Manganese(III)-promoted oxidative free-radical cyclizations of β-keto imides: Asymmetric induction with oppolzer's chiral sultam

Philip A. Zoretic, Xiaoyu Weng, Christopher K. Bíggers et al. · Tetrahedron Letters · 1992 · 45 citations

Biochemistry, β-Keto Imides, Natural Sciences +7

General Preparation of 7-Substituted 4-Chromanones: Synthesis of a Potent Aldose Reductase Inhibitor

Kevin M. Koch, Michael S. Biggers · The Journal of Organic Chemistry · 1994 · 42 citations

Altmetric Attention Score, Organic Chemistry, Pharmaceutical Chemistry +16