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Inverse Agonism and Neutral Antagonism at Wild-Type and Constitutively Active Mutant Delta Opioid Receptors

Petra Tóth, Fabien M. Décaillot, Dominique Filliol, Katia Befort, L. H. Lazarus, Peter W. Schiller, Helmut Schmidhammer, Brigitte L. Kieffer

Journal of Pharmacology and Experimental Therapeutics · 2005 · 31 citations · 32 references

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32

Mice deficient for δ- and μ-opioid receptors exhibit opposing alterations of emotional responses

Dominique Filliol, Sandy Ghozland, Johanna Chluba et al. · Nature Genetics · 2000 · 668 citations

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Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins.

Tommaso Costa, A. Herz · Proceedings of the National Academy of Sciences · 1989 · 530 citations · Full text

, , +15

Peptides Chemistry, Structure and Biology

Jean Rivier, Garland R. Marshall · 1990 · 510 citations

, , +12

A Single Nucleotide Polymorphic Mutation in the Human μ-Opioid Receptor Severely Impairs Receptor Signaling

Katia Befort, Dominique Filliol, Fabien M. Décaillot et al. · Journal of Biological Chemistry · 2001 · 243 citations · Full text

, , +17

Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists.

Peter W. Schiller, Tin Nguyen, Grazyna Weltrowska et al. · Proceedings of the National Academy of Sciences · 1992 · 240 citations · Full text

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