Concepedia

Intrinsic Activity

Intrinsic Activity is a pharmacological property that quantifies the maximum efficacy of a ligand in activating a receptor relative to a reference full agonist, distinguishing it from affinity by measuring the capacity to produce a functional response upon receptor binding.

1.7K

Publications

134.4K

Citations

8.7K

Authors

1.8K

Institutions

Publications per year

2017–2026

662

Parents

Publications

1.7K

Cobalt–Iron (Oxy)hydroxide Oxygen Evolution Electrocatalysts: The Role of Structure and Composition on Activity, Stability, and Mechanism

Michaela S. Burke, Matthew G. Kast, Lena Trotochaud et al. · Journal of the American Chemical Society · 2015 · 1.9K citations · Full text

, , +17

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

A. De Léan, Jeffrey M. Stadel, Robert J. Lefkowitz · Journal of Biological Chemistry · 1980 · 1.6K citations · Full text

, , +17

Catalyzing the Hydrogen Evolution Reaction (HER) with Molybdenum Sulfide Nanomaterials

Jesse D. Benck, Thomas R. Hellstern, Jakob Kibsgaard et al. · ACS Catalysis · 2014 · 1.6K citations

, , +17

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.

Philippe Samama, Susanna Cotecchia, Tommaso Costa et al. · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text

, , +17

Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model

Hayrünnisa Bolay, Uwe Reuter, Andrew K. Dunn et al. · Nature Medicine · 2002 · 1.2K citations

, , +16

1–5 of 1.7K

Authors

8.7K

  1. SW
    Shuangyin Wang

    Hunan University, China

    11 publications · 2.6K citations

    11

    h-index

  2. AP
    Adriaan P. IJzerman

    Centre for Human Drug Research, Netherlands

    10 publications · 640 citations

    10

    h-index

  3. RJ
    Robert J. Lefkowitz

    Duke Medical Center, United States

    10 publications · 4.2K citations

    10

    h-index

  4. MM
    Marco Mor

    University of Parma, Italy

    9 publications · 393 citations

    9

    h-index

  5. GS
    Gilberto Spadoni

    University of Urbino, Italy

    9 publications · 417 citations

    9

    h-index

1–5 of 8.7K

Institutions

1.8K

  1. Chinese Academy of Sciences

    Beijing, China

    53 h-index

    397 publications

    58.4K citations

  2. University of Science and Technology of China

    Hefei, China

    36 h-index

    318 publications

    43.6K citations

  3. University of Chinese Academy of Sciences

    Beijing, China

    33 h-index

    126 publications

    10.3K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    25 h-index

    146 publications

    6.8K citations

  5. Tianjin University

    Tianjin, China

    21 h-index

    112 publications

    8.7K citations

  6. Tsinghua University

    Beijing, China

    20 h-index

    70 publications

    7.6K citations

  7. Washington University in St. Louis

    St Louis, United States

    18 h-index

    49 publications

    4.4K citations

  8. Hunan University

    Changsha, China

    18 h-index

    134 publications

    22.7K citations

1–8 of 1.8K

Venues

  1. Angewandte Chemie International Edition

    52 publications · 9.4K citations

    43

    h-index

  2. Journal of Biological Chemistry

    JBC · 49 publications · 8K citations

    37

    h-index

  3. 36

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 40 publications · 6.1K citations

    36

    h-index

  5. ACS Catalysis

    40 publications · 5.9K citations

    32

    h-index

1–5