Concepedia

Receptor Theory

Receptor Theory is a pharmacodynamic framework that explains drug action as the result of specific, reversible, and saturable interactions between drugs and cellular receptors, with the magnitude and nature of the response determined by the affinity of the drug for the receptor and its intrinsic efficacy upon receptor occupancy.

232

Publications

25.2K

Citations

569

Authors

225

Institutions

Publications per year

2017–2026

17

Variants

Receptor Occupancy Theory

Parents

Children

Publications

232

Receptors for Purines and Pyrimidines

Geoffrey Burnstock, Alexei Verkhratsky · 2012 · 4K citations

, , +10

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

O. ARUNLAKSHANA, H. O. Schild · British Journal of Pharmacology and Chemotherapy · 1959 · 4K citations · Full text

, , +16

A MODIFICATION OF RECEPTOR THEORY

R. P. STEPHENSON · British Journal of Pharmacology and Chemotherapy · 1956 · 1.1K citations · Full text

, , +15

Operational models of pharmacological agonism

J.W. Black, P. Leff · Proceedings of the Royal Society of London. Series B, Biological sciences · 1983 · 1.1K citations

, , +16

Structure and function of an irreversible agonist-β2 adrenoceptor complex

Daniel M. Rosenbaum, Cheng Zhang, Joseph A. Lyons et al. · Nature · 2011 · 773 citations · Full text

, , +12

1–5 of 232

Authors

569

  1. TK
    Terry Kenakin

    Research Triangle Park Foundation, United States

    4 publications · 123 citations

    4

    h-index

  2. RJ
    Ronald J. Tallarida

    Temple University, United States

    3 publications · 81 citations

    3

    h-index

  3. SE
    Susan E. Cozzens

    Georgia Institute of Technology, United States

    3 publications · 66 citations

    3

    h-index

  4. CD
    Charles DeLisi

    Boston University, United States

    3 publications · 195 citations

    3

    h-index

  5. AE
    Ariëns Ej

    Radboud University Nijmegen, Netherlands

    3 publications · 163 citations

    3

    h-index

1–5 of 569

Institutions

225

  1. National Institutes of Health

    Bethesda, United States

    6 h-index

    13 publications

    4K citations

  2. Research Triangle Park Foundation

    Durham, United States

    6 h-index

    8 publications

    1.1K citations

  3. Los Alamos National Laboratory

    Los Alamos, United States

    4 h-index

    5 publications

    317 citations

  4. Temple University

    Philadelphia, United States

    4 h-index

    9 publications

    603 citations

  5. University College London

    London, United Kingdom

    4 h-index

    6 publications

    8.2K citations

  6. Stanford University

    Stanford, United States

    3 h-index

    10 publications

    4.9K citations

  7. University of California, Irvine

    Irvine, United States

    3 h-index

    7 publications

    553 citations

  8. Icahn School of Medicine at Mount Sinai

    New York, United States

    3 h-index

    13 publications

    3.5K citations

1–8 of 225

Venues

  1. PubMed

    Repository · 18 publications · 757 citations

    14

    h-index

  2. Trends in Pharmacological Sciences

    12 publications · 458 citations

    12

    h-index

  3. 10

    h-index

  4. British Journal of Pharmacology

    BJP · 7 publications · 518 citations

    7

    h-index

  5. Journal of Medicinal Chemistry

    7 publications · 433 citations

    7

    h-index

1–5