Receptors for Purines and Pyrimidines

Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold.

John E. Walker, M Saraste, M J Runswick et al. · The EMBO Journal · 1982 · 5.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

G. V. R. Born · Nature · 1962 · 4.3K citations

Medicine, Biochemistry, Hematology +14

The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints

Robert Fredriksson, Malin C. Lagerström, Lars‐Gustav Lundin et al. · Molecular Pharmacology · 2003 · 2.9K citations

Life Sciences, Genetics, Molecular Biology +13

The 2.6 Angstrom Crystal Structure of a Human A _2A Adenosine Receptor Bound to an Antagonist

Veli‐Pekka Jaakola, Mark T. Griffith, Michael A. Hanson et al. · Science · 2008 · 1.8K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The Cytolytic P _2Z Receptor for Extracellular ATP Identified as a P _2X Receptor (P2X ₇ )

Annmarie Surprenant, Eric Kawashima, R. Alan North et al. · Science · 1996 · 1.7K citations

Life Sciences, Biochemistry, Pharmacology +15