Concepedia
Statistics
Publications
101
Citations
6.9K
H-Index
39
Active since
1979
Affiliations
Istituto Superiore di Sanità(Current)
Max Planck Institute of Psychiatry
National Institutes of Health
Kyushu University
Max Planck Institute of Biochemistry
Tommaso Costa is an author at Istituto Superiore di Sanità specializing in pharmacology, receptor pharmacology, and medicine.
Publications per year
1979–2021
A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.
Philippe Samama, Susanna Cotecchia, Tommaso Costa et al. · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text
Life Sciences, Molecular Biology, Pharmacology +17
Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins.
Tommaso Costa, A. Herz · Proceedings of the National Academy of Sciences · 1989 · 530 citations · Full text
Medicine, Molecular Biology, Pharmacology +15
Constitutively active mutants of the alpha 1B‐adrenergic receptor: role of highly conserved polar amino acids in receptor activation.
Alexander Scheer, Francesca Fanelli, Tommaso Costa et al. · The EMBO Journal · 1996 · 392 citations · Full text
Medicine, Biochemistry, Pharmacology +13
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
Dean P. Staus, Ryan T. Strachan, Aashish Manglik et al. · Nature · 2016 · 328 citations · Full text
Life Sciences, Biophysics, Molecular Biology +17
Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand.
Tommaso Costa, Yukiko Ogino, Peter J. Munson et al. · Molecular Pharmacology · 1992 · 242 citations
Medicine, Molecular Biology, Pharmacology +17
1–5 of 101