A. De Léan

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

A. De Léan, Jeffrey M. Stadel, Robert J. Lefkowitz · Journal of Biological Chemistry · 1980 · 1.6K citations · Full text

Agonist-specific Binding Properties, Experimental Pharmacology, Ternary Complex Hrx +17

Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes.

A. De Léan, Arthur A. Hancock, Robert J. Lefkowitz · Molecular Pharmacology · 1982 · 594 citations

Drug Target, Radioligand Binding Data, Medicine +8

Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.

Jacques Drouin, Yu Sun, Michel Chamberland et al. · The EMBO Journal · 1993 · 325 citations · Full text

Molecular Physiology, Endocrine Mechanism, Medicine +10

Anterior pituitary dopamine receptors. Demonstration of interconvertible high and low affinity states of the D-2 dopamine receptor.

David R. Sibley, A. De Léan, Ian Creese · Journal of Biological Chemistry · 1982 · 295 citations · Full text

Neurotransmitter, Pharmacotherapy, Medicinal Chemistry +20

Modulation of Pituitary Thyrotropin Releasing Hormone Receptor Levels by Estrogens and Thyroid Hormones

A. De Léan, Louise Ferland, Jacques Drouin et al. · Endocrinology · 1977 · 227 citations

Pituitary Gland, Endocrine Mechanism, Medicine +12