Concepedia

Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo

Yongbo Zhao, Peng Luo, Qindong Guo, Sanzhong Li, Lei Zhang, Mingming Zhao, Haoxiang Xu, Yuefan Yang, Wai Sang Poon, Zhou Fei

Experimental Neurology · 2012 · 132 citations · 45 references

DOI

Concepts

References

45

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

Matt Kaeberlein, Mitch McVey, Leonard Guarente · Genes & Development · 1999 · 2.3K citations · Full text

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Evolutionarily Conserved and Nonconserved Cellular Localizations and Functions of Human SIRT Proteins

Eriko Michishita, Jean Y. Park, Jenna M. Burneskis et al. · Molecular Biology of the Cell · 2005 · 1.4K citations · Full text

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Nucleocytoplasmic Shuttling of the NAD+-dependent Histone Deacetylase SIRT1

Masaya Tanno, Jun Sakamoto, Tetsuji Miura et al. · Journal of Biological Chemistry · 2007 · 763 citations · Full text

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SIRT1 Improves Insulin Sensitivity under Insulin-Resistant Conditions by Repressing PTP1B

Cheng Sun, Fang Zhang, Xinjian Ge et al. · Cell Metabolism · 2007 · 754 citations · Full text

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SIRT1 Protects against Microglia-dependent Amyloid-β Toxicity through Inhibiting NF-κB Signaling

Jennifer Chen, Yungui Zhou, Sarah Mueller-Steiner et al. · Journal of Biological Chemistry · 2005 · 737 citations · Full text

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