DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology · 1992 · 9.5K citations · Full text

Dna Damage, Apoptosis, Dna Analysis +16

Crystal structure of the nucleosome core particle at 2.8 Å resolution

Karolin Luger, Armin W. Mäder, Robin K. Richmond et al. · Nature · 1997 · 9.3K citations

Nucleosome Core Particle, Crystal Structure, Engineering +10

DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

Emmy P. Rogakou, Duane R. Pilch, Ann H. Orr et al. · Journal of Biological Chemistry · 1998 · 5.3K citations · Full text

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

Chromatin, Genome Instability, Dna Damage +6

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

Gerrit Koopman, CP Reutelingsperger, GA Kuijten et al. · Blood · 1994 · 2.5K citations · Full text