Publication | Closed Access

Non-Peptidic inhibitors of human chymase. Synthesis, structure–activity relationships, and pharmacokinetic profiles of a series of 5-amino-6-oxo-1,6-dihydropyrimidine-containing trifluoromethyl ketones

Medicinal ChemistryBiochemistryHuman ChymaseMedicineNatural SciencesStructure–activity RelationshipsDrug DevelopmentPharmacologyPharmaceutical ChemistryInhibitory ActivityDrug DiscoveryNon-peptidic Inhibitors