Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart.

H Urata, Ayaka Kinoshita, K S Misono, +2

Journal of Biological Chemistry

Cardiac MuscleHeart FailureHuman Heart ChymaseHuman HeartNeutral Serine Proteinase +15

Angiotensin II-forming pathways in normal and failing human hearts.

H Urata, Bernadine Healy, Robert W. Stewart, +2

Circulation Research

Ang Ii FormationHypertensionHeart FailureAce InhibitorsCardiomyopathy +13

Cellular localization and regional distribution of an angiotensin II-forming chymase in the heart.

H Urata, Keith D. Boehm, Anie Philip, +4

Journal of Clinical Investigation

Cardiac MuscleCardiomyopathyAngiotensin IiCellular LocalizationPhysiology +12

Antihypertensive and volume-depleting effects of mild exercise on essential hypertension.

H Urata, Yuuhiko Tanabe, Akira Kiyonaga, +4

Hypertension

HypertensionPhysical ActivityMild ExerciseWhole BloodBlood Pressure +17

Cloning of the gene and cDNA for human heart chymase.

H Urata, Ayaka Kinoshita, Dianne M. Perez, +4

Journal of Biological Chemistry

Cardiac MuscleChymotrypsin-like Serine ProteinaseGeneticsHuman Heart ChymaseMolecular Genetics +17

Multiple determinants for the high substrate specificity of an angiotensin II-forming chymase from the human heart.

Ayaka Kinoshita, H Urata, F. Merlin Bumpus, +1

Journal of Biological Chemistry

Angiotensin Ii-forming ChymaseHuman Heart ChymaseAng IiCardiovascular FunctionHigh Substrate Specificity +16

Effect of acute exercise on plasma immunoreactive — atrial natriuretic factor

Hirofumi Tanaka, Munehiro Shindo, Jolanta Gutkowska, +4

Life Sciences

Physical ActivityCardiovascular DiseaseExerciseExercise PhysiologyPhysiology +10

Widespread tissue distribution of human chymase.

H Urata, Fabian Strobel, D Ganten

PubMed

Angiotensins and the failing heart. Enhanced positive inotropic response to angiotensin I in cardiomyopathic hamster heart in the presence of captopril.

Hiroyuki HIRAKATA, Fetnat M. Fouad-Tarazi, F. Merlin Bumpus, +5

Circulation Research

Cardiac MuscleHypertensionHeart FailureAngiotensin IiCardiomyopathy +13

Measurement of angiotensin I converting enzyme inhibition in the heart.

Ayaka Kinoshita, H Urata, F. Merlin Bumpus, +1

Circulation Research