Naoko Mitsutomi

Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphate

Masatoshi Kiuchi, Kunitomo Adachi, Ayumi Tomatsu et al. · Bioorganic & Medicinal Chemistry · 2004 · 71 citations · Full text

Immunosuppressive Fty720-phosphate, Biosynthesis, Bioorganic Chemistry +8

Synthesis, Structure−Activity Relationships, and Pharmacokinetic Profiles of Nonpeptidic Difluoromethylene Ketones as Novel Inhibitors of Human Chymase

Fumihiko Akahoshi, Atsuyuki Ashimori, Hiroshi Sakashita et al. · Journal of Medicinal Chemistry · 2001 · 38 citations · Full text

Medicinal Chemistry, Nonpeptidic Difluoromethylene Ketones, Pharmaceutical Science +15

Synthesis, Structure−Activity Relationships, and Pharmacokinetic Profiles of Nonpeptidic α-Keto Heterocycles as Novel Inhibitors of Human Chymase

Fumihiko Akahoshi, Atsuyuki Ashimori, Hiroshi Sakashita et al. · Journal of Medicinal Chemistry · 2001 · 29 citations · Full text

Human Chymase, Nonpeptidic Chymase Inhibitors, Pharmaceutical Chemistry +16

Non-Peptidic inhibitors of human chymase. Synthesis, structure–activity relationships, and pharmacokinetic profiles of a series of 5-amino-6-oxo-1,6-dihydropyrimidine-containing trifluoromethyl ketones

Fumihiko Akahoshi, Atsuyuki Ashimori, Takuya Yoshimura et al. · Bioorganic & Medicinal Chemistry · 2001 · 14 citations

Medicinal Chemistry, Biochemistry, Human Chymase +9