Concepedia

RagA, but Not RagB, Is Essential for Embryonic Development and Adult Mice

Alejo Efeyan, Lawrence D. Schweitzer, Angelina M. Bilate, Steven H. Chang, Oktay Kirak, Dudley W. Lamming, David M. Sabatini

Developmental Cell · 2014 · 89 citations · 25 references

DOIFull text

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References

25

Autophagy fights disease through cellular self-digestion

Noboru Mizushima, Beth Levine, Ana María Cuervo et al. · Nature · 2008 · 6.4K citations · Full text

, , +14

Metabolite profiles and the risk of developing diabetes

Thomas J. Wang, Martin G. Larson, Ramachandran S. Vasan et al. · Nature Medicine · 2011 · 3.1K citations · Full text

, , +12

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Yasemin Sancak, Timothy R. Peterson, Yoav D. Shaul et al. · Science · 2008 · 2.8K citations

, , +14

Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Dos D. Sarbassov, Siraj M. Ali, Shomit Sengupta et al. · Molecular Cell · 2006 · 2.6K citations · Full text

, , +6

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

Yasemin Sancak, Liron Bar‐Peled, Roberto Zoncu et al. · Cell · 2010 · 2.4K citations · Full text

, , +17