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Preparation of 1-(3-aminobenzo[d]isoxazol-5-yl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective, and efficacious inhibitors of coagulation factor Xa

Medicinal ChemistryPharmaceutical ScienceBiochemistryAntiparasitic AgentMedicineNatural SciencesEfficacious InhibitorsPharmacological AgentPharmacotherapyDrug DevelopmentCoagulation Factor XaPharmacologyPharmaceutical ChemistryDrug Discovery