Donald Pinto

Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans

Nirmala Raghavan, Charles Frost, Zhigang Yu et al. · Drug Metabolism and Disposition · 2008 · 598 citations

Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase.

Robert A. Copeland, Jean Williams, John Giannaras et al. · Proceedings of the National Academy of Sciences · 1994 · 410 citations · Full text

Aldo-keto Reductase, Molecular Biology, Pharmacotherapy +19

Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro- 1<i>H</i>-pyrazolo[3,4-<i>c</i>]pyridine-3-carboxamide (Apixaban, BMS-562247), a Highly Potent, Selective, Efficacious, and Orally Bioavailable Inhibitor of Blood Coagulation Factor Xa

Donald Pinto, Michael J. Orwat, Stephanie C. Koch et al. · Journal of Medicinal Chemistry · 2007 · 391 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Primary Aniline +15

125I-labelled fibrinogen in the diagnosis of deep-vein thrombosis and its correlation with phlebography

David Negus, Donald Pinto, L P Le Quesne et al. · British journal of surgery · 1968 · 310 citations

Pathology, Surgery, Thrombosis +24

Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies

Pancras C. Wong, Earl J. Crain, Bailong Xin et al. · Journal of Thrombosis and Haemostasis · 2008 · 299 citations · Full text

Thrombopoiesis, Thrombosis, Medicinal Chemistry +8