Expressions of amyloid precursor protein, synaptophysin and presenilin-1 in the different areas of the developing cerebellum of rat

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature · 1998 · 1.8K citations

Life Sciences, Molecular Biology, Neuroscience +15

The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology

Cynthia A. Lemere, Kenneth S. Kosik, Corrine L. Lendon et al. · Nature Medicine · 1996 · 487 citations

Life Sciences, Neurology, Neuroscience +14

Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact.

Brenda D. Shivers, C. Hilbich, Gerd Multhaup et al. · The EMBO Journal · 1988 · 441 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

Lennart Mucke, Eliezer Masliah, William B. Johnson et al. · Brain Research · 1994 · 274 citations

Life Sciences, Neurobiology, Neuroscience +16

Localization of Alzheimer βA4 amyloid precursor protein at central and peripheral synaptic sites

Walter Schubert, Reinhard Prior, Andreas Weidemann et al. · Brain Research · 1991 · 261 citations

Life Sciences, Neurobiology, Neuroscience +14