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Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4

BiochemistryMetabolic ActivationMedicinePsychotropic MedicationExperimental PharmacologyEpoxide IntermediatesHuman Liver MicrosomesMetabolomicsPharmacologyDrug Discovery