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Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21 Cip

Manuel Blandino-Rosano, Emilyn U. Alejandro, Aruna Sathyamurthy, Joshua O. Scheys, Brandon S. Gregg, A. Y. Chen, Latif Rachdi, Aaron Weiss, Daniel Barker, Alex P. Gould,

Diabetologia · 2012 · 21 citations · 46 references

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46

Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation

Yuval Dor, Juliana Brown, Olga I. Martinez et al. · Nature · 2004 · 2.2K citations

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Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Han Cho, James Mu, Jason K. Kim et al. · Science · 2001 · 1.8K citations

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Disruption of IRS-2 causes type 2 diabetes in mice

Dominic J. Withers, Julio Sanchez Gutierrez, Heather Towery et al. · Nature · 1998 · 1.8K citations

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

S Waga, Gregory J. Hannon, David Beach et al. · Nature · 1994 · 1.7K citations

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New functional activities for the p21 family of CDK inhibitors.

Joshua LaBaer, Michelle D. Garrett, Lauren Stevenson et al. · Genes & Development · 1997 · 1.4K citations · Full text

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