The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.6K citations

Molecular Pharmacology, G1 Cyclin-dependent Kinases, Signal Transduction +10

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Manuel Serrano, Gregory J. Hannon, David Beach · Nature · 1993 · 3.7K citations

Specific Inhibition, Transcriptional Regulation, Signal Transduction +14

p21 is a universal inhibitor of cyclin kinases

Yue Xiong, Gregory J. Hannon, Hui Zhang et al. · Nature · 1993 · 3.4K citations

Receptor Tyrosine Kinase, Cyclin Kinases, Anti-cancer Agent +4

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell · 1992 · 3.1K citations

Genome Instability, Cell Regulation, Cell Death +5