Concepedia

Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK111Abbreviations: CDK, cyclin-dependent kinase; CKI, CDK inhibitor; PI 3-kinase, phosphatidylinositol 3-kinase; PKC, protein kinase C; DTT, dithiothreitol; RIPA, radioimmunoprecipitation assay buffer.

Fabrice Casagrande, Jean-Marie Darbon

Biochemical Pharmacology · 2001 · 304 citations · 46 references

DOI

Concepts

References

46

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Tetsu Akiyama, Junko Ishida, Shizue Nakagawa et al. · Journal of Biological Chemistry · 1987 · 3.7K citations · Full text

, , +15

Dietary Flavonoids and the Risk of Lung Cancer and Other Malignant Neoplasms

Paul Knekt, R. J rvinen, R. Sepp nen et al. · American Journal of Epidemiology · 1997 · 773 citations

, , +16

Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.

Bradley A. Carlson, M M Dubay, Edward A. Sausville et al. · PubMed · 1996 · 537 citations

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Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis.

T. Fotsis, Michael S. Pepper, Stephen Breit et al. · PubMed · 1997 · 536 citations

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Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition

Georgine Agullo, Laurence Gamet‐Payrastre, Stéphane Manenti et al. · Biochemical Pharmacology · 1997 · 536 citations

, , +16