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Stereoselective synthesis of 11-phenylundeca-5Z,9Z-dienoic acid and investigation of its human topoisomerase I and IIα inhibitory activity

Vladimir A. D’yakonov, Lilya U. Dzhemileva, Aleksey A. Makarov, Alfiya R. Mulukova, Dmitry S. Baev

Bioorganic & Medicinal Chemistry Letters · 2015 · 44 citations · 18 references

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18

The mechanism of topoisomerase I poisoning by a camptothecin analog

Bart L. Staker, Kathryn A. Hjerrild, M.D. Feese et al. · Proceedings of the National Academy of Sciences · 2002 · 802 citations · Full text

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On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs

Chyuan-Chuan Wu, Yi-Ching Li, Wang Ying-Ren et al. · Nucleic Acids Research · 2013 · 189 citations · Full text

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Novel Angular Benzophenazines:  Dual Topoisomerase I and Topoisomerase II Inhibitors as Potential Anticancer Agents

Nigel Vicker, Luke Burgess, Irina Chuckowree et al. · Journal of Medicinal Chemistry · 2002 · 133 citations

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Design, Synthesis, and Biological Evaluation of 14-Substituted Aromathecins as Topoisomerase I Inhibitors

Maris A. Cinelli, Andrew Morrell, Thomas S. Dexheimer et al. · Journal of Medicinal Chemistry · 2008 · 83 citations · Full text

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Design, Synthesis, and Evaluation of Dibenzo[<i>c,h</i>][1,6]naphthyridines as Topoisomerase I Inhibitors and Potential Anticancer Agents

Evgeny Kiselev, Thomas S. Dexheimer, Yves Pommier et al. · Journal of Medicinal Chemistry · 2010 · 76 citations · Full text

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