Structure−Activity Relationships for Pyrido-, Imidazo-, Pyrazolo-, Pyrazino-, and Pyrrolophenazinecarboxamides as Topoisomerase-Targeted Anticancer Agents

Swarna A. Gamage, Julie A. Spicer, Gordon W. Rewcastle, +7

Journal of Medicinal Chemistry

Pharmaceutical SciencePharmacotherapyPharmaceutical ChemistryDrug ResistanceMedicinal Chemistry +14

Novel Angular Benzophenazines:  Dual Topoisomerase I and Topoisomerase II Inhibitors as Potential Anticancer Agents

Nigel Vicker, Luke Burgess, Irina Chuckowree, +15

Journal of Medicinal Chemistry

Medicinal ChemistryPharmaceutical ChemistryBioorganic ChemistryChemoprevention StrategyMedicine +13

Selective Type IV Phosphodiesterase Inhibitors as Antiasthmatic Agents. The Syntheses and Biological Activities of 3-(Cyclopentyloxy)-4-methoxybenzamides and Analogs

Michael J. Ashton, David Cook, Garry Fenton, +5

Journal of Medicinal Chemistry

Antiparasitic AgentPde IvBiological ActivitiesPharmacotherapyPharmaceutical Chemistry +15

17β‐hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone‐dependent breast cancer

Joanna M. Day, Paul Foster, Helena J. Tutill, +9

International Journal of Cancer

Synthesis of strychnine via the Wieland-Gumlich aldehyde

P. Magnus, Melvyn Giles, Roger V. Bonnert, +4

Journal of the American Chemical Society

Molecular SciencesChemical MeasurementChemical AnalysisDonut IconAltmetric Attention Score +6

E-Ring Modified Steroids as Novel Potent Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1

Delphine S. Fischer, G.M. Allan, Christian Bubert, +9

Journal of Medicinal Chemistry

Studies on Pyrrolopyrimidines as Selective Inhibitors of Multidrug-Resistance- Associated Protein in Multidrug Resistance

Shouming Wang, Adrian Folkes, Irina Chuckowree, +14

Journal of Medicinal Chemistry

Drug TargetMultidrug ResistanceSelective InhibitorsPharmacotherapyAntimicrobial Chemotherapy +15

Synthesis of strychnine and the Wieland-Gumlich aldehyde

P. Magnus, Melvyn Giles, Roger V. Bonnert, +6

Journal of the American Chemical Society

Molecular SciencesChemical AnalysisBiochemistryDonut IconNatural Sciences +9

Studies on the synthesis of Strychnos alkaloids. A new entry into the azocino[4,3-b]indole core structure and related studies

Philip Magnus, Nancy L. Sear, Chung S. Kim, +1

The Journal of Organic Chemistry

Related StudiesBioorganic ChemistryBiochemistryDonut IconNatural Sciences +13

Modification of Estrone at the 6, 16, and 17 Positions:  Novel Potent Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1

G.M. Allan, Harshani R. Lawrence, Joséphine Cornet, +10

Journal of Medicinal Chemistry