Michael J. Ashton

Selective Type IV Phosphodiesterase Inhibitors as Antiasthmatic Agents. The Syntheses and Biological Activities of 3-(Cyclopentyloxy)-4-methoxybenzamides and Analogs

Michael J. Ashton, David Cook, Garry Fenton et al. · Journal of Medicinal Chemistry · 1994 · 112 citations · Full text

Antiparasitic Agent, Pde Iv, Biological Activities +17

Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP‐specific phosphodiesterase: comparison with rolipram

John E. Soilness, Christopher Maslen, Stephen E. Webber et al. · British Journal of Pharmacology · 1995 · 85 citations · Full text

New perspectives in lead generation II: Evaluating molecular diversity

Michael J. Ashton, Michael Jaye, Jon S. Mason · Drug Discovery Today · 1996 · 54 citations

Hit Identification, Molecular Biology, Lead Identification +2

The absorption, metabolism and excretion of disodium cromoglycate in nine animal species

Michael J. Ashton, Barbara J. Clark, K. M. Jones et al. · Toxicology and Applied Pharmacology · 1973 · 50 citations

Animal Physiology, Biochemistry, Food Digestion +7

Anti-inflammatory 17β-Thioalkyl-16α,17α-ketal and -acetal Androstanes:  A New Class of Airway Selective Steroids for the Treatment of Asthma

Michael J. Ashton, Christopher Lawrence, Jan‐Anders Karlsson et al. · Journal of Medicinal Chemistry · 1996 · 39 citations · Full text

Asthma, Inflammatory Lung Disease, Lung Inflammation +17