Thomas S. Dexheimer

An Intramolecular G-Quadruplex Structure with Mixed Parallel/Antiparallel G-Strands Formed in the Human BCL-2 Promoter Region in Solution

Jixun Dai, Thomas S. Dexheimer, Megan Carver et al. · Journal of the American Chemical Society · 2006 · 406 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Deconvoluting the Structural and Drug-Recognition Complexity of the G-Quadruplex-Forming Region Upstream of the <i>bcl-2</i> P1 Promoter

Thomas S. Dexheimer, Daekyu Sun, Laurence H. Hurley · Journal of the American Chemical Society · 2006 · 391 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

Liang Qin, Thomas S. Dexheimer, Ping Zhang et al. · Nature Chemical Biology · 2014 · 273 citations

Life Sciences, Genetics, Molecular Biology +10

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy

William C. Stafford, Xiaoxiao Peng, Maria Hägg Olofsson et al. · Science Translational Medicine · 2018 · 243 citations · Full text

Medicine, Oncology, Pharmacology +5

Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition

Michael V. Gormally, Thomas S. Dexheimer, Giovanni Marsico et al. · Nature Communications · 2014 · 222 citations · Full text

Life Sciences, Genetics, Molecular Biology +14