William C. Stafford

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy

William C. Stafford, Xiaoxiao Peng, Maria Hägg Olofsson et al. · Science Translational Medicine · 2018 · 243 citations · Full text

Medicine, Oncology, Pharmacology +5

The 19S Deubiquitinase Inhibitor b-AP15 Is Enriched in Cells and Elicits Rapid Commitment to Cell Death

Xin Wang, William C. Stafford, Magdalena Mazurkiewicz et al. · Molecular Pharmacology · 2014 · 63 citations

Medicine, Cancer Biology, Oncology +14

Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay

Stefanie Prast‐Nielsen, Thomas S. Dexheimer, Lena Schultz et al. · Free Radical Biology and Medicine · 2011 · 44 citations

Life Sciences, Biochemistry, Medicinal Chemistry +13

Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells

Marijke C.C. Sachweh, William C. Stafford, Catherine J. Drummond et al. · Oncotarget · 2015 · 35 citations · Full text

Medicine, Oncology, Pharmacology +17

Indolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leads

Kamila Kaminska, Hélène Bertrand, Hisashi Tajima et al. · Oncotarget · 2016 · 27 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9