Functional binding assays for estimation of the intrinsic efficacy of ligands at the 5-HT1A receptor: Application for screening drug candidates

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

A. De Léan, Jeffrey M. Stadel, Robert J. Lefkowitz · Journal of Biological Chemistry · 1980 · 1.6K citations · Full text

Medicine, Biochemistry, Pharmacology +17

Intuitive Biostatistics.

R. A. Brown, H. Motulsky · Biometrics · 1997 · 803 citations

[³H]8‐Hydroxy‐2‐(Di‐<i>n</i>‐Propylamino)Tetralin Binding to Pre‐ and Postsynaptic 5‐Hydroxytryptamine Sites in Various Regions of the Rat Brain

M.D. Hall, Salah El Mestikawy, M.B. Emerit et al. · Journal of Neurochemistry · 1985 · 459 citations

Life Sciences, Neurobiology, Neuroscience +15

Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a []GTPγS binding study

Adrian Newman‐Tancredi, Samantha Gavaudan, Caroline Conte et al. · European Journal of Pharmacology · 1998 · 226 citations

Medicine, Pharmacology, Psychiatry +13

Receptor–ligand binding assays: Technologies and Applications

Lutea A. A. de Jong, Donald R. A. Uges, Jan Piet Franke et al. · Journal of Chromatography B · 2005 · 202 citations

Life Sciences, Molecular Biology, Pharmacology +12