Concepedia

Ligand-binding Assays

Ligand-Binding Assay is a bioanalytical method that quantifies the specific interaction between a biomolecule and its binding partner by measuring the extent of selective molecular recognition and affinity-based complex formation under defined experimental conditions.

1.9K

Publications

129.3K

Citations

9.1K

Authors

2.1K

Institutions

Publications per year

2017–2026

345

Variants

LbaLbasLigand-binding Assay

Parents

Publications

1.9K

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

Peter J. Munson, David Rodbard · Analytical Biochemistry · 1980 · 8.5K citations

, , +11

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

Edgar Schreiber, Patrick Matthias, Michael M. Müller et al. · Nucleic Acids Research · 1989 · 4.2K citations · Full text

, , +9

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

F. Niesen, H. Berglund, Masoud Vedadi · Nature Protocols · 2007 · 2.4K citations

, , +14

The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

Andrew J. Brown, Susan M. Goldsworthy, Ashley Barnes et al. · Journal of Biological Chemistry · 2003 · 2.3K citations · Full text

, , +17

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

Moriz Mayer, Bernd Meyer · Angewandte Chemie International Edition · 1999 · 1.6K citations

, , +16

1–5 of 1.9K

Authors

9.1K

  1. KT
    Klaus T. Wanner

    Ludwig-Maximilians-Universität München, Germany

    14 publications · 350 citations

    12

    h-index

  2. GH
    Georg Höfner

    Ludwig-Maximilians-Universität München, Germany

    12 publications · 268 citations

    11

    h-index

  3. EN
    Elena N. Kitova

    University of Alberta, Canada

    10 publications · 632 citations

    10

    h-index

  4. BD
    Binodh DeSilva

    Bristol-Myers Squibb (United States), United States

    10 publications · 895 citations

    10

    h-index

  5. JS
    John S. Klassen

    University of Alberta, Canada

    10 publications · 632 citations

    10

    h-index

1–5 of 9.1K

Institutions

2.1K

  1. Centre National de la Recherche Scientifique

    Paris, France

    27 h-index

    215 publications

    10.7K citations

  2. Harvard University

    Cambridge, United States

    26 h-index

    88 publications

    16.6K citations

  3. National Institutes of Health

    Bethesda, United States

    24 h-index

    125 publications

    24.7K citations

  4. Inserm

    Paris, France

    23 h-index

    124 publications

    5.3K citations

  5. Pfizer (United States)

    New York, United States

    19 h-index

    100 publications

    3.6K citations

  6. Chinese Academy of Sciences

    Beijing, China

    18 h-index

    113 publications

    4.8K citations

  7. University of Alberta

    Edmonton, Canada

    18 h-index

    84 publications

    4.7K citations

  8. Bristol-Myers Squibb (United States)

    New York, United States

    18 h-index

    133 publications

    7.3K citations

1–8 of 2.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 93 publications · 11.1K citations

    54

    h-index

  2. Journal of Medicinal Chemistry

    64 publications · 3.5K citations

    37

    h-index

  3. Analytical Chemistry

    69 publications · 3.4K citations

    36

    h-index

  4. Analytical Biochemistry

    68 publications · 12.8K citations

    31

    h-index

  5. Journal of the American Chemical Society

    JACS · 36 publications · 3.1K citations

    28

    h-index

1–5