Receptor-Ligand Selectivity is a biochemical interaction specificity that governs the preferential binding of cargo receptors to particular ligands based on molecular compatibility, ensuring accurate sorting and trafficking of substrates within cellular transport pathways.
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Structure of the CCR5 Chemokine Receptor–HIV Entry Inhibitor Maraviroc Complex
Qiuxiang Tan, Ya Zhu, Jian Li et al. · Science · 2013 · 716 citations · Full text
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- PGPeter Gmeiner
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
10 publications · 425 citations
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National Institutes of Health
Bethesda, United States
32 h-index
217 publications
11K citations
Centre National de la Recherche Scientifique
Paris, France
25 h-index
159 publications
9.4K citations
Inserm
Paris, France
24 h-index
160 publications
8.4K citations
National Institute on Drug Abuse
Bethesda, United States
21 h-index
144 publications
7K citations
University of Cambridge
Cambridge, United Kingdom
21 h-index
75 publications
3.9K citations
National Institute of Diabetes and Digestive and Kidney Diseases
Bethesda, United States
20 h-index
80 publications
6.1K citations
Howard Hughes Medical Institute
Chevy Chase, United States
19 h-index
72 publications
5.7K citations
University of Arizona
Tucson, United States
19 h-index
149 publications
12.3K citations
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- Journal of Medicinal Chemistry
216 publications · 9.7K citations
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- Journal of Biological Chemistry
JBC · 97 publications · 8K citations
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- Molecular Pharmacology
84 publications · 5.4K citations
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- Proceedings of the National Academy of Sciences
PNAS · 40 publications · 6.7K citations
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- Journal of Pharmacology and Experimental Therapeutics
67 publications · 4.4K citations
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