Concepedia

Ligand-based Screening

Ligand-Based Screening is a computational drug repurposing approach that identifies new therapeutic uses for existing drugs by analyzing the structural and physicochemical similarities between known active ligands and candidate compounds, distinguishing it from target-based methods through its reliance on ligand similarity rather than protein target information.

790

Publications

39.6K

Citations

4.2K

Authors

1.2K

Institutions

Publications per year

2017–2026

334

Variants

LbvsLigand-based Virtual Screening

Parents

Publications

790

ZINC 15 – Ligand Discovery for Everyone

Teague Sterling, John J. Irwin · Journal of Chemical Information and Modeling · 2015 · 3.4K citations · Full text

, , +13

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Wesley K. Kroeze, Maria F. Sassano, Xi‐Ping Huang et al. · Nature Structural & Molecular Biology · 2015 · 785 citations · Full text

, , +9

Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

Erin M. Bowers, Gai Yan, Chandrani Mukherjee et al. · Chemistry & Biology · 2010 · 655 citations · Full text

, , +16

A Common Reference Framework for Analyzing/Comparing Proteins and Ligands. Fingerprints for Ligands And Proteins (FLAP):  Theory and Application

Massimo Baroni, Gabriele Cruciani, Simone Sciabola et al. · Journal of Chemical Information and Modeling · 2007 · 436 citations

, , +17

SwissSimilarity: A Web Tool for Low to Ultra High Throughput Ligand-Based Virtual Screening

Vincent Zoete, Antoine Daina, Christophe Bovigny et al. · Journal of Chemical Information and Modeling · 2016 · 400 citations

, , +17

1–5 of 790

Authors

4.2K

  1. MO
    Mutasem O. Taha

    University of Jordan, Jordan

    12 publications · 353 citations

    12

    h-index

  2. JR
    Jean‐Louis Reymond

    University of Bern, Switzerland

    9 publications · 577 citations

    9

    h-index

  3. CD
    Claudio Dalvit

    Novartis (Switzerland), Switzerland

    9 publications · 1.2K citations

    9

    h-index

  4. NS
    Naomie Salim

    University of Technology Malaysia, Malaysia

    9 publications · 263 citations

    9

    h-index

  5. GS
    Gisbert Schneider

    ETH Zurich, Switzerland

    8 publications · 373 citations

    8

    h-index

1–5 of 4.2K

Institutions

1.2K

  1. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    95 publications

    6K citations

  2. University of Jordan

    Amman, Jordan

    13 h-index

    31 publications

    1.1K citations

  3. Inserm

    Paris, France

    13 h-index

    46 publications

    5.5K citations

  4. Goethe University Frankfurt

    Frankfurt am Main, Germany

    13 h-index

    74 publications

    3.1K citations

  5. Universidade de São Paulo

    São Paulo, Brazil

    12 h-index

    75 publications

    2.6K citations

  6. Chinese Academy of Sciences

    Beijing, China

    11 h-index

    47 publications

    2.3K citations

  7. Université Paris Cité

    Paris, France

    10 h-index

    39 publications

    4.1K citations

  8. University of Cambridge

    Cambridge, United Kingdom

    10 h-index

    24 publications

    2K citations

1–8 of 1.2K

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 114 publications · 10.1K citations

    46

    h-index

  2. Journal of Medicinal Chemistry

    65 publications · 4K citations

    40

    h-index

  3. Scientific Reports

    21 publications · 781 citations

    19

    h-index

  4. Journal of Biomolecular Structure and Dynamics

    23 publications · 639 citations

    16

    h-index

  5. Bioorganic & Medicinal Chemistry Letters

    22 publications · 612 citations

    16

    h-index

1–5