Maria F. Sassano

Structure-based discovery of opioid analgesics with reduced side effects

Aashish Manglik, Henry J. Lin, Dipendra K. Aryal et al. · Nature · 2016 · 925 citations · Full text

Health Sciences, Pain Medicine, Structure-based Discovery +8

Automated design of ligands to polypharmacological profiles

Jérémy Besnard, G.F. Ruda, Vincent Setola et al. · Nature · 2012 · 832 citations · Full text

Engineering, Ligand-based Drug Design, Drug Design +8

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Wesley K. Kroeze, Maria F. Sassano, Xi‐Ping Huang et al. · Nature Structural & Molecular Biology · 2015 · 746 citations · Full text

Open-source Resource, Translational Bioinformatics, Medicine +8

Discovery of β-Arrestin–Biased Dopamine D ₂ Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy

John Allen, Julianne M. Yost, Vincent Setola et al. · Proceedings of the National Academy of Sciences · 2011 · 351 citations

Chronic E-Cigarette Exposure Alters the Human Bronchial Epithelial Proteome

Arunava Ghosh, Raymond C. Coakley, Teresa Mascenik et al. · American Journal of Respiratory and Critical Care Medicine · 2018 · 236 citations · Full text