Concepedia

High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia

Ahmed Achouiti, Anne Jan van der Meer, Sandrine Florquin, Huan Yang, Kevin J. Tracey, Cornelis van ′t Veer, Alex F. de Vos, Tom van der Poll

Critical Care · 2013 · 49 citations · 21 references

DOIFull text

Open access

Abstract

These data suggest that HMGB1 and RAGE, but not TLR4, contribute to lung injury accompanying the early phase of S. aureus pneumonia.

References

21

Invasive Methicillin-Resistant <EMPH TYPE="ITAL">Staphylococcus aureus</EMPH> Infections in the United States

R. Monina Klevens · JAMA · 2007 · 3.7K citations

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product

Katsuaki Hoshino, Osamu Takeuchi, Taro Kawai et al. · The Journal of Immunology · 1999 · 3.4K citations · Full text

Severe Community-Onset Pneumonia in Healthy Adults Caused by Methicillin-Resistant Staphylococcus aureus Carrying the Panton-Valentine Leukocidin Genes

John S. Francis, Meg Doherty, Uri Lopatin et al. · Clinical Infectious Diseases · 2004 · 716 citations

Cutting Edge: HMG-1 as a Mediator of Acute Lung Inflammation

Edward Abraham, John J. Arcaroli, Aaron Carmody et al. · The Journal of Immunology · 2000 · 689 citations · Full text

HMGB1 release induced by liver ischemia involves Toll-like receptor 4–dependent reactive oxygen species production and calcium-mediated signaling

Allan Tsung, John R. Klune, Xianghong Zhang et al. · The Journal of Experimental Medicine · 2007 · 604 citations · Full text

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