John R. Klune

HMGB1 release induced by liver ischemia involves Toll-like receptor 4–dependent reactive oxygen species production and calcium-mediated signaling

Allan Tsung, John R. Klune, Xianghong Zhang et al. · The Journal of Experimental Medicine · 2007 · 604 citations · Full text

Immunology, Cell Death, Redox Biology +20

High Mobility Group Box 1 Release from Hepatocytes during Ischemia and Reperfusion Injury Is Mediated by Decreased Histone Deacetylase Activity

John Evankovich, Sung W. Cho, Ruilin Zhang et al. · Journal of Biological Chemistry · 2010 · 235 citations · Full text

Noninvasive radiofrequency ablation of cancer targeted by gold nanoparticles

Jon Cardinal, John R. Klune, Eamon Chory et al. · Surgery · 2008 · 200 citations · Full text

Nanoparticles, Nanomedicine, Engineering +3

Hepatocyte-Specific High-Mobility Group Box 1 Deletion Worsens the Injury in Liver Ischemia/Reperfusion: A Role for Intracellular High-Mobility Group Box 1 in Cellular Protection

Hai Huang, Gary Nace, Kerry-Ann McDonald et al. · Hepatology · 2013 · 144 citations · Full text

Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury

Allan Tsung, Ning Zheng, Geetha Jeyabalan et al. · Journal of Leukocyte Biology · 2006 · 118 citations