Edward Abraham

HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Haichao Wang, Ona Bloom, Minghuang Zhang et al. · Science · 1999 · 3.4K citations

Veterinary Medicine, Immunology, Pathology +17

Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein

Jong Sung Park, Daiva Svetkauskaite, Qianbin He et al. · Journal of Biological Chemistry · 2004 · 1.6K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Treatment of Septic Shock with the Tumor Necrosis Factor Receptor:Fc Fusion Protein

Charles J. Fisher, Jan M. Agosti, Steven M. Opal et al. · New England Journal of Medicine · 1996 · 1.3K citations

Veterinary Medicine, Immunology, Infectious Diseases +12

Efficacy and Safety of Tifacogin (Recombinant Tissue Factor Pathway Inhibitor) in Severe Sepsis

Edward Abraham, Konrad Reinhart, Steven M. Opal et al. · JAMA · 2003 · 957 citations

Medicine, Pharmacology, Pharmacotherapy +15

High mobility group box 1 protein interacts with multiple Toll-like receptors

Jong Sung Park, Fabia Gamboni-Robertson, Qianbin He et al. · American Journal of Physiology-Cell Physiology · 2005 · 939 citations

Life Sciences, Immunology, Molecular Biology +17