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Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and c-erbB-2

Stuart Cockerill, Colin Stubberfield, Jeremy N. Stables, Malcolm Carter, Stephen B. Guntrip, Kathryn J. Smith, Steve C. McKeown, Robert J. Shaw, Peter Topley, Lindy L. Thomsen,

Bioorganic & Medicinal Chemistry Letters · 2001 · 80 citations · 8 references

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8

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.7K citations

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Tyrosine Kinase Inhibitors. 8. An Unusually Steep Structure−Activity Relationship for Analogues of 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a Potent Inhibitor of the Epidermal Growth Factor Receptor

Alexander J. Bridges, Hairong Zhou, Donna R. Cody et al. · Journal of Medicinal Chemistry · 1996 · 322 citations · Full text

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Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor:  4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-<i>d</i>]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions

Jeff B. Smaill, Gordon W. Rewcastle, Joseph A. Loo et al. · Journal of Medicinal Chemistry · 2000 · 265 citations · Full text

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Binding Mode of the 4-Anilinoquinazoline Class of Protein Kinase Inhibitor:  X-ray Crystallographic Studies of 4-Anilinoquinazolines Bound to Cyclin-Dependent Kinase 2 and p38 Kinase

Lisa M. Shewchuk, Anne M. Hassell, Bruce Wisely et al. · Journal of Medicinal Chemistry · 1999 · 236 citations · Full text

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Tyrosine Kinase Inhibitors. 10. Isomeric 4-[(3-Bromophenyl)amino]pyrido[<i>d</i>]- pyrimidines Are Potent ATP Binding Site Inhibitors of the Tyrosine Kinase Function of the Epidermal Growth Factor Receptor

Gordon W. Rewcastle, Brian D. Palmer, Andrew M. Thompson et al. · Journal of Medicinal Chemistry · 1996 · 114 citations · Full text

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