Wiskott-Aldrich Syndrome Protein-Deficient Mice Reveal a Role for WASP in T but Not B Cell Activation

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Catherine D. Nobes, Alan Hall · Cell · 1995 · 4.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

Veterinary Medicine, Immunology, Infectious Diseases +14

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

Benjamin Sadlack, Hartmut Merz, Hubert Schorle et al. · Cell · 1993 · 1.7K citations

Veterinary Medicine, Immunology, Pathology +14

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

Medicine, Genetics, Molecular Genetics +15

Redistribution and Pinocytosis of Lymphocyte Surface Immunoglobulin Molecules Induced by Anti-Immunoglobulin Antibody

Roger B. Taylor, W. P. H. Duffus, Martin Raff et al. · Nature New Biology · 1971 · 1.1K citations

Life Sciences, Cell Biology, Immunology +11