Wiskott-Aldrich Syndrome Protein-Deficient Mice Reveal a Role for WASP in T but Not B Cell Activation

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Catherine D. Nobes, Alan Hall · Cell · 1995 · 4.4K citations · Full text

Actin Stress Fibers, Protein Function, Signal Transduction +13

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

Inflammation, Cytokine, Autoimmune Disease +6

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

Benjamin Sadlack, Hartmut Merz, Hubert Schorle et al. · Cell · 1993 · 1.7K citations

Inflammation, Chronic Inflammatory Diseases, Ulcerative Colitis-like Disease +10

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

Knockout Mouse, Embryonic Stem Cell, Lineage Plasticity +12

Redistribution and Pinocytosis of Lymphocyte Surface Immunoglobulin Molecules Induced by Anti-Immunoglobulin Antibody

Roger B. Taylor, W. P. H. Duffus, Martin Raff et al. · Nature New Biology · 1971 · 1.1K citations

Immunocytochemical Technique, Autoimmune Disease, Allergy +13