Concepedia

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

Benjamin Sadlack, Hartmut Merz, Hubert Schorle, Anneliese Schimpl, Alfred C. Feller, Ivan D. Horak

Cell · 1993 · 1.7K citations · 32 references

DOI

Concepts

References

32

Establishment in culture of pluripotential cells from mouse embryos

Martin Evans, M. H. Kaufman · Nature · 1981 · 8.6K citations

, , +14

RAG-1-deficient mice have no mature B and T lymphocytes

Peter Mombaerts, John Iacomini, Randall S. Johnson et al. · Cell · 1992 · 2.9K citations

, , +13

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Yoichi Shinkai · Cell · 1992 · 2.6K citations

, , +14

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

, , +12

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

Peter Mombaerts, Alan R. Clarke, Michael A. Rudnicki et al. · Nature · 1992 · 1.1K citations

, , +16