Wiskott-Aldrich Syndrome Protein-Deficient Mice Reveal a Role for WASP in T but Not B Cell Activation

Scott B. Snapper, Fred S. Rosen, Emiko Mizoguchi, +9

Immunity

Signal TransductionAutoimmune DiseaseT-regulatory CellImmunologyB Cell Activation +6

Mapping of the X-linked agammaglobulinemia locus by use of restriction fragment-length polymorphism.

Sau‐Ping Kwan, Louis M. Kunkel, G.A.P. Bruns, +3

Journal of Clinical Investigation

Restriction Fragment-length PolymorphismLinkage DisequilibriumAllelic VariantGenetic DisorderGenetics +12

Mutations of the humanBTK gene coding for bruton tyrosine kinase in X-linked agammaglobulinemia

Mauno Vihinen, Sau‐Ping Kwan, Tracy Lester, +4

Human Mutation

X-linked AgammaglobulinemiaGeneticsHumanbtk GenePathologyMolecular Genetics +15

Fusion of Mouse Myeloma and Spleen Cells

D E Yelton, Betty Diamond, Sau‐Ping Kwan, +1

HematologyImmunologyBlood CellMouse MyelomaMedicine +2

Identification of mutations in the Wiskott-Aldrich syndrome gene and characterization of a polymorphic dinucleotide repeat at DXS6940, adjacent to the disease gene.

Sau‐Ping Kwan, Tracy L. Hagemann, B E Radtke, +2

Proceedings of the National Academy of Sciences

Allelic VariantMendelian DisorderWiskott-aldrich Syndrome GeneGenetic DisorderX Chromosome +13

Multiple immunoglobulin switch region homologies outside the heavy chain constant region locus

Ilan R. Kirsch, Jeffrey V. Ravetch, Sau‐Ping Kwan, +3

Nature

ImmunogeneticsSignal TransductionAutoimmune DiseaseImmunodeficienciesGenetics +7

Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA).

Qili Zhu, Miqin Zhang, David J. Rawlings, +8

The Journal of Experimental Medicine

Genomic organization of the <i>Btk</i> gene and exon scanning for mutations in patients with X-linked agammaglobulinemia

Tracy L. Hagemann, Yuexin Chen, Fred S. Rosen, +1

Human Molecular Genetics

Primary ImmunodeficiencyX-linked AgammaglobulinemiaGenomic OrganizationSomatic VariantGenetic Disorder +12

Identification of a closely linked DNA marker, DXS178, to further refine the X-linked agammaglobulinemia locus

Sau‐Ping Kwan, Joseph D. Terwilliger, Robin Parmley, +6

Genomics

Genetic DisorderGeneticsPathologyMolecular GeneticsDisease Gene Identification +5

Genetic mapping of the Wiskott-Aldrich syndrome with two highly-linked polymorphic DNA markers

Sau‐Ping Kwan, L. A. Sandkuyl, Michael Blaese, +7

Genomics

Mendelian DisorderGenetic DisorderGeneticsMolecular BiologyMolecular Genetics +5