Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

Molecular Cloning. A Laboratory Manual

EJ Wood · Biochemical Education · 1983 · 30.6K citations

Molecular Biological Method, Natural Sciences, Genetics +8

T cell tolerance by clonal elimination in the thymus

John W. Kappler, Neal W. Roehm, Philippa Marrack · Cell · 1987 · 2.2K citations

T Cell Tolerance, Autoimmune Disease, Allergy +8

A Theory of Self-Nonself Discrimination

Peter A. Bretscher, Melvin Cohn · Science · 1970 · 1.7K citations

Discrimination, Immunology, Immunologic Mechanism +23

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice

Christopher C. Goodnow, J. Crosbie, Stephen Adelstein et al. · Nature · 1988 · 1.6K citations

Autoimmune Disease, Lymphocyte Development, Immunology +9

Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

Ralph L. Brinster, H Y Chen, Myrna E. Trumbauer et al. · Proceedings of the National Academy of Sciences · 1985 · 1K citations · Full text

Fertility, Genetics, Molecular Genetics +16