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Inhibition of HIV-1 capsid assembly: Optimization of the antiviral potency by site selective modifications at N1, C2 and C16 of a 5-(5-furan-2-yl-pyrazol-1-yl)-1H-benzimidazole scaffold

Martin Tremblay, Pierre Bonneau, Yves Bousquet, Patrick DeRoy, Jianmin Duan, Martin Duplessis, Alexandre Gagnon, Michel Garneau, Nathalie Goudreau, Ingrid Guse,

Bioorganic & Medicinal Chemistry Letters · 2012 · 36 citations · 16 references

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References

16

X-Ray Structures of the Hexameric Building Block of the HIV Capsid

Owen Pornillos, Barbie K. Ganser‐Pornillos, Brian N. Kelly et al. · Cell · 2009 · 541 citations · Full text

, , +16

Formation of a Human Immunodeficiency Virus Type 1 Core of Optimal Stability Is Crucial for Viral Replication

Brett M. Forshey, Uta von Schwedler, Wesley I. Sundquist et al. · Journal of Virology · 2002 · 519 citations · Full text

, , +17

Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein

Uta K. von Schwedler, Kirsten M. Stray, Jennifer Garrus et al. · Journal of Virology · 2003 · 422 citations · Full text

, , +17

Atomic-level modelling of the HIV capsid

Owen Pornillos, Barbie K. Ganser‐Pornillos, Mark Yeager · Nature · 2011 · 381 citations · Full text

, , +14

Assembly Properties of the Human Immunodeficiency Virus Type 1 CA Protein

Barbie K. Ganser‐Pornillos, Uta K. von Schwedler, Kirsten M. Stray et al. · Journal of Virology · 2004 · 306 citations · Full text

, , +17