Martin Duplessis

Identification of (<i>R</i>)-<i>N</i>-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1<i>H</i>-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas

Rishi G. Vaswani, Victor Gehling, Les A. Dakin et al. · Journal of Medicinal Chemistry · 2016 · 220 citations · Full text

Medicine, Oncology, Pharmacology +16

Identification of a genetic determinant responsible for host specificity in <i>Streptococcus thermophilus</i> bacteriophages

Martin Duplessis, Sylvain Moineau · Molecular Microbiology · 2001 · 180 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +15

Arylcyclopropanes: Properties, Synthesis and Use in Medicinal Chemistry

Alexandre Gagnon, Martin Duplessis, Lee D. Fader · Organic Preparations and Procedures International · 2010 · 125 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains

Terry D. Crawford, Vickie Tsui, E. Megan Flynn et al. · Journal of Medicinal Chemistry · 2016 · 118 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Genomic Organization and Molecular Analysis of Virulent Bacteriophage 2972 Infecting an Exopolysaccharide-Producing <i>Streptococcus thermophilus</i> Strain

Céline M. Lévesque, Martin Duplessis, Jessica Labonté et al. · Applied and Environmental Microbiology · 2005 · 87 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16