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An oxygen-regulated switch in the protein synthesis machinery

James Uniacke, Chet E. Holterman, Gabriel Lachance, Aleksandra Franovic, Mathieu D. Jacob, Marc R. Fabian, Josianne Payette, Martin Holčı́k, Arnim Pause, Stephen Lee

Nature · 2012 · 335 citations · 24 references

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24

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

, , +17

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan, Keiichi Kondo, Haifeng Yang et al. · Science · 2001 · 4.7K citations · Full text

, , +16

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

Markus Hafner, Markus Landthaler, Lukas Burger et al. · Cell · 2010 · 3K citations · Full text

, , +15

Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude

Xin Yi, Yu Liang, Emilia Huerta‐Sánchez et al. · Science · 2010 · 1.7K citations · Full text

, , +13

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

James Brugarolas, Kui Lei, Rebecca L. Hurley et al. · Genes & Development · 2004 · 1.4K citations · Full text

, , +17