Stephen Lee

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

Arnim Pause, Stephen Lee, Robert Worrell et al. · Proceedings of the National Academy of Sciences · 1997 · 499 citations · Full text

Silencing of Epidermal Growth Factor Receptor Suppresses Hypoxia-Inducible Factor-2–Driven <i>VHL</i> −/− Renal Cancer

Karlene Smith, Lakshman Gunaratnam, Melissa Morley et al. · Cancer Research · 2005 · 457 citations · Full text

An oxygen-regulated switch in the protein synthesis machinery

James Uniacke, Chet E. Holterman, Gabriel Lachance et al. · Nature · 2012 · 323 citations · Full text

Biochemistry, Protein Folding, Natural Sciences +7

Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer

Aleksandra Franovic, Lakshman Gunaratnam, Karlene Smith et al. · Proceedings of the National Academy of Sciences · 2007 · 278 citations · Full text

HIF activation by pH-dependent nucleolar sequestration of VHL

Karim Mekhail, Lakshman Gunaratnam, Marie-Eve Bonicalzi et al. · Nature Cell Biology · 2004 · 256 citations

Signal Transduction, Biochemistry, Molecular Regulation +8