Karim Mekhail

Silencing of Epidermal Growth Factor Receptor Suppresses Hypoxia-Inducible Factor-2–Driven <i>VHL</i> −/− Renal Cancer

Karlene Smith, Lakshman Gunaratnam, Melissa Morley et al. · Cancer Research · 2005 · 457 citations · Full text

HIF activation by pH-dependent nucleolar sequestration of VHL

Karim Mekhail, Lakshman Gunaratnam, Marie-Eve Bonicalzi et al. · Nature Cell Biology · 2004 · 256 citations

Signal Transduction, Biochemistry, Molecular Regulation +8

Role for perinuclear chromosome tethering in maintenance of genome stability

Karim Mekhail, Jan Seebacher, Steven P. Gygi et al. · Nature · 2008 · 243 citations · Full text

Chromatin, Genome Instability, Genome Stability +5

Nucleolar RNA polymerase II drives ribosome biogenesis

Karan Joshua Abraham, Negin Khosraviani, Janet N.Y. Chan et al. · Nature · 2020 · 204 citations · Full text

Transcriptional Regulation, Ribosome Biogenesis, Rna Biology +5

Hypoxia Inducible Factor Activates the Transforming Growth Factor-α/Epidermal Growth Factor Receptor Growth Stimulatory Pathway in VHL-/- Renal Cell Carcinoma Cells

Lakshman Gunaratnam, Melissa Morley, Aleksandra Franovic et al. · Journal of Biological Chemistry · 2003 · 186 citations · Full text