Discovery of highly potent triazole antifungal derivatives by heterocycle-benzene bioisosteric replacement

Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen

Gareth Jones, Peter Willett, Robert C. Glen et al. · Journal of Molecular Biology · 1997 · 6.7K citations

Pharmacy, Bioinformatics, Medicinal Chemistry +14

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

Nicholas A. Meanwell · Journal of Medicinal Chemistry · 2011 · 2.8K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Synthesis and Photovoltaic Properties of Two-Dimensional Conjugated Polythiophenes with Bi(thienylenevinylene) Side Chains

Jianhui Hou, Zhan’ao Tan, Yong Yan et al. · Journal of the American Chemical Society · 2006 · 780 citations

Natural Sciences, Chemistry, Materials Science +17

Amphotericin B: Time for a New "Gold Standard"

Louis D. Saravolatz, Luis Ostrosky‐Zeichner, Kieren A. Marr et al. · Clinical Infectious Diseases · 2003 · 406 citations

Pharmacy, Pharmacotherapy, Antimicrobial Pharmacology +15

Yeast cytochrome P-450 catalyzing lanosterol 14 alpha-demethylation. II. Lanosterol metabolism by purified P-450(14)DM and by intact microsomes.

Yuri Aoyama, Yuichi Yoshida, Ryosuke Sato · Journal of Biological Chemistry · 1984 · 211 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16