Guoqiang Dong

Aptamer‐PROTAC Conjugates (APCs) for Tumor‐Specific Targeting in Breast Cancer

Shipeng He, Fei Gao, Junhui Ma et al. · Angewandte Chemie International Edition · 2021 · 259 citations

Breast Oncology, Bet-targeting Protac, Tumor Biology +17

Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents

Shengzheng Wang, Kun Fang, Guoqiang Dong et al. · Journal of Medicinal Chemistry · 2015 · 189 citations · Full text

Medicinal Chemistry, Natural Product Synthesis, Diversity Oriented Synthesis +13

New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

Guoqiang Dong, Shengzheng Wang, Zhenyuan Miao et al. · Journal of Medicinal Chemistry · 2012 · 179 citations

Pharmaceutical Science, Old Natural Product, Novel Antitumor Agents +17

Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor Agents

Guoqiang Dong, Chunquan Sheng, Shengzheng Wang et al. · Journal of Medicinal Chemistry · 2010 · 145 citations

Pharmaceutical Science, Bioorganic Chemistry, Chemoprevention Strategy +19

Potent Dual BET/HDAC Inhibitors for Efficient Treatment of Pancreatic Cancer

Shipeng He, Guoqiang Dong, Yu Li et al. · Angewandte Chemie International Edition · 2020 · 140 citations