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BACE1 inhibitors: A head group scan on a series of amides

Thomas J. Woltering, Wolfgang Wostl, Hans Hilpert, Mark Rogers‐Evans, Emmanuel Pinard, A. Mayweg, Martin Göbel, David W. Banner, Jörg Benz, Massimiliano Travagli,

Bioorganic & Medicinal Chemistry Letters · 2013 · 52 citations · 7 references

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7

MAB, a generally applicable molecular force field for structure modelling in medicinal chemistry

Paul R. Gerber, Klaus M�ller · Journal of Computer-Aided Molecular Design · 1995 · 595 citations

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Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor

Patrick C. May, Robert A. Dean, Stephen L. Lowe et al. · Journal of Neuroscience · 2011 · 369 citations · Full text

, , +16

Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor

Jared N. Cumming, Elizabeth M. Smith, Lingyan Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 154 citations · Full text

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Pharmacological Promiscuity: Dependence on Compound Properties and Target Specificity in a Set of Recent Roche Compounds

Jens‐Uwe Peters, Patrick Schnider, Patrizio Mattei et al. · ChemMedChem · 2009 · 151 citations

, , +11

β-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease

Hans Hilpert, Wolfgang Guba, Thomas J. Woltering et al. · Journal of Medicinal Chemistry · 2013 · 137 citations · Full text

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