Emmanuel Pinard

Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( <i>SMN2</i> ) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)

Hasane Ratni, Martin Ebeling, John D. Baird et al. · Journal of Medicinal Chemistry · 2018 · 520 citations · Full text

Medicine, Neurology, Pharmacology +14

β-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease

Hans Hilpert, Wolfgang Guba, Thomas J. Woltering et al. · Journal of Medicinal Chemistry · 2013 · 137 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((<i>S</i>)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia

Emmanuel Pinard, Alexander Alanine, Daniela Alberati et al. · Journal of Medicinal Chemistry · 2010 · 134 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia

Daniela Alberati, Jean‐Luc Moreau, Judith A. Lengyel et al. · Neuropharmacology · 2011 · 126 citations

Medicine, Pharmacology, Psychiatry +10

A Real-World Perspective on Molecular Design

Bernd Kuhn, Wolfgang Guba, Jérôme Hert et al. · Journal of Medicinal Chemistry · 2016 · 120 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17