Concepedia

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

Mark H. Kaplan, Ya‐Lin Sun, Timothy Hoey, Michael J. Grusby

Nature · 1996 · 1.2K citations · 20 references

DOI

Concepts

References

20

Development of T <sub>H</sub> 1 CD4 <sup>+</sup> T Cells Through IL-12 Produced by <i>Listeria</i> -Induced Macrophages

Chyi‐Song Hsieh, S E Macatonia, Catherine S. Tripp et al. · Science · 1993 · 3.1K citations

, , +17

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.

Michiko Kobayashi, Lori Fitz, Michael P. Ryan et al. · The Journal of Experimental Medicine · 1989 · 2K citations · Full text

, , +14

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

Roberto Manetti, Paola Parronchi, M G Giudizi et al. · The Journal of Experimental Medicine · 1993 · 1.7K citations · Full text

, , +17

Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway

Marco Antonio Meraz‐Ríos, J. Michael White, Kathleen C. F. Sheehan et al. · Cell · 1996 · 1.7K citations · Full text

, , +9

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

Vijay K. Kuchroo, Mercy Prabhu Das, Julia A. Brown et al. · Cell · 1995 · 1.7K citations · Full text

, , +15